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折扣/货期| 货号：24161-1 mg | 规格：1 mg | 目录价：￥482 |
| 货号：24161-10 mg | 规格：10 mg | 目录价：￥2265 |
| 货号：24161-25 mg | 规格：25 mg | 目录价：￥5065 |
| 货号：24161-5 mg | 规格：5 mg | 目录价：￥1273 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Takinib
产品描述:
A TAK1 inhibitor (IC50 = 9.5 nM); selective for TAK1 over IRAK1, IRAK4, GCK, Clk2, and MINK1 (IC50s = 390, 120, 430, 430, and 1,900 nM, respectively); increases caspase-3/-7 activity and inhibits proliferation of TNF-α-stimulated, but not unstimulated, MDA-MB-231 cells; reduces phosphorylation of IKK, p38 MAPK, MAPK8, MAPK9, and c-Jun in TNF-α-stimulated MDA-MB-231 cells; inhibits IL-6 secretion in TNF-α-stimulated rheumatoid arthritis fibroblast-like synoviocytes; reduces inflammation and cartilage damage in knee joints in a mouse model of collagen type II-induced arthritis at 50 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
322.4
产品形式:
A solid
纯度:
≥98%
CAS号:
1111556-37-6
分子式:
C18H18N4O2
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