| 货号:29699-100 mg | 规格:100 mg | 目录价:¥1206 |
| 货号:29699-250 mg | 规格:250 mg | 目录价:¥2492 |
| 货号:29699-500 mg | 规格:500 mg | 目录价:¥4677 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Talnetant
别名:
SB-223412
产品描述:
A nonpeptide NK3 antagonist (Ki = 1 nM); selective for NK3 over NK1 and NK2 receptors (Kis = 144 and >100,000 nM, respectively, in CHO cells expressing recombinant human receptors); inhibits neurokinin B-induced calcium mobilization in HEK293 cells expressing human NK3 receptors (IC50 = 16.6 nM); inhibits senktide-induced contractions in isolated rabbit iris sphincter muscle (pD2 = 9.1); reduces senktide-induced head shakes and tail whips in mice from 5-20 mg/kg; inhibits senktide-induced wet-dog shakes, increases extracellular dopamine and norepinephrine in the medial prefrontal cortex, and attenuates haloperidol-induced increases in nucleus accumbens dopamine levels in guinea pigs
保存温度:
-20
运输温度:
-20
预期分子量:
382.45446
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
174636-32-9
分子式:
C25H22N2O2
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