官网链接
折扣/货期| 货号：40454-10 mg | 规格：10 mg | 目录价：￥2492 |
| 货号：40454-25 mg | 规格：25 mg | 目录价：￥5574 |
| 货号：40454-5 mg | 规格：5 mg | 目录价：￥1313 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
TCH-165
产品描述:
A proteasome assembly modulator; selectively activates the chymotrypsin-like, trypsin-like, and caspase-like activities of the 20S proteasome (EC50s = 4.2, 3.2, and 4.7 µM, respectively) over the same activities of the 26S proteasome (EC50s = >70 µM for all) but also inhibits the chymotrypsin-like activity of the 20S proteasome (IC50 = 1.44 µM) in cell-free assays; increases the 20S proteasome-dependent degradation of α-synuclein and tau at 10 µM; enhances disassembly of the 26S proteasome with a concomitant increase in 20S proteasome levels in HEK293T cells; decreases tumor volume in an RPMI-8226 multiple myeloma mouse xenograft model at 100 mg/kg, p.o.; decreases infarct volume as a percentage of the area at risk in a mouse model of cardiac ischemia-reperfusion injury induced by left anterior descending coronary artery occlusion at a 50 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
595.7295
产品形式:
A solid
纯度:
≥98%
CAS号:
1446350-60-2
分子式:
C39H37N3O3
促销活动
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