Telmisartan-激动剂-深圳欣博盛生物科技有限公司

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Telmisartan

品牌：Adipogen

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说明书

折扣/货期

货号：CDX-T0460-M010	规格：10 mg	目录价：￥462
货号：CDX-T0460-M050	规格：50 mg	目录价：￥1386

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Telmisartan

别名:

BIBR 277; Micardis; Pritor; 4'[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl][1,1'-biphenyl]-2-carboxylic acid

产品描述:

Telmisartan is a nonpeptide angiotensin II receptor antagonist which selectively inhibits the angiotensin II AT1 receptor subtype (Ki=3.7nM). Telmisartan exhibits antihypertensive activity in a renin-dependent model of hypertension. In addition to blocking the renin-angiotensin system (RAS), telmisartan acts as a selective modulator of peroxisome proliferator-activated receptor gamma (PPAR-gamma), a central regulator of insulin and glucose metabolism and improving insulin sensitivity. It is believed that telmisartan's dual mode of action may provide protective benefits against the vascular and renal damage caused by diabetes and cardiovascular disease (CVD). Through these actions, telmisartan potently reduces blood pressure in various animal models of hypertension, diminishing cardiac hypertrophy, cardiovascular and renal risk and glomerulosclerosis. Furthermore, telmisartan inhibits proliferation in several cancer models by inducing apoptosis and cell cycle arrest.

宿主来源:

Synthetic

保存温度:

+20°C

运输温度:

Ambient

预期分子量:

514.62

产品形式:

solid

产地:

瑞士