深圳欣博盛生物科技有限公司 a1

TH-302
货号:22195-1 mg 规格:1 mg 目录价:¥590
货号:22195-10 mg 规格:10 mg 目录价:¥4074
货号:22195-25 mg 规格:25 mg 目录价:¥8697
货号:22195-5 mg 规格:5 mg 目录价:¥2479
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
TH-302
别名:
Evofosfamide
产品描述:
A hypoxia-activated prodrug and DNA alkylating agent with anticancer activity; selectively cytotoxic to H460 human NSCLC cells grown under hypoxic over normoxic conditions (IC50s = 0.019 and 5.1 μM, respectively); reduces survival of H460 and HT-29 cells in a clonogenic assay (IC50s = 0.2 and 0.2 μM, respectively); inhibits primary tumor growth by 41% in an MIA PaCa-2-RFP mouse orthotopic xenograft model at 33 mg/kg per day; inhibits tumor growth in the Calu-6 NSCLC, H82 small cell lung, A375 melanoma, PC-3 prostate, and BxPC-3 pancreatic cancer mouse xenograft models at 50 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
449
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
918633-87-1
分子式:
C9H16Br2N5O4P
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