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折扣/货期| 货号：45380-1 mg | 规格：1 mg | 目录价：￥1273 |
| 货号：45380-10 mg | 规格：10 mg | 目录价：￥8911 |
| 货号：45380-5 mg | 规格：5 mg | 目录价：￥5413.6 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
TH9619
产品描述:
An MTHFD inhibitor (IC50s = 16, 47, and 47 nM, respectively); inhibits nuclear MTHFD2 and cytoplasmic MTHFD1 but not mitochondrial MTHFD2, leading to an increase in 10-CHO-THF, thymidylate depletion, and cell death; selective for MTHFD1 and MTHFD2 over a panel of 44 kinases at 12 µM; reduces proliferation in a panel of AML cells; impairs DNA replication in HL-60 and THP-1 cells at 50 nM; increases survival in an HL-60 mouse xenograft model at 30 mg/kg twice per day in combination with a low-folate diet
保存温度:
-20
运输温度:
-20
预期分子量:
451.371403
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
2379556-22-4
分子式:
C17H18FN7O7
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