深圳欣博盛生物科技有限公司 a1

Thiomyristoyl
货号:19398-10 mg 规格:10 mg 目录价:¥643
货号:19398-25 mg 规格:25 mg 目录价:¥1112
货号:19398-50 mg 规格:50 mg 目录价:¥1903
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Thiomyristoyl
别名:
TM
产品描述:
A potent and selective SIRT2 inhibitor (IC50s = 0.028, 98, >200, and >200 μM for SIRT2, SIRT1, SIRT3, and SIRT5-7, respectively); inhibits acetyl-H3K9 peptide and NAD binding to SIRT2 and promotes c-Myc degradation in a dose-dependent manner; exhibits selective cytotoxicity (IC50s = 8.4-36.8 and >50 μM for cancerous and non-cancerous cell lines, respectively); decreases tumor volume and increases areas of necrosis in an MDA-MB-231 mouse breast cancer xenograft model; increases tumor-free survival time in a MMTV-PyMT mouse mammary tumor model
保存温度:
-20
运输温度:
-20
预期分子量:
581.9
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1429749-41-6
分子式:
C34H51N3O3S
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