Thioredoxin Antibody / TXN / TRX-多抗-深圳欣博盛生物科技有限公司

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Thioredoxin Antibody / TXN / TRX

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：F40029-0.08ML	规格：0.08 ml	目录价：￥2962.25
货号：F40029-0.4ML	规格：0.4 ml	目录价：￥6343.55

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Thioredoxin Antibody / TXN / TRX

产品描述:

Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide targets for reduction by Trx include protein disulfide _x0013_isomerase(PDI) and a number of transcription factors such as p53, NF-kB and AP-1.Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.

反应种属:

Human

宿主来源:

Rabbit

实验应用:

WB, ELISA

同种型:

Rabbit Ig

免疫原:

A portion of amino acids 1-30 from the human protein was used as the immunogen for this Thioredoxin antibody.

克隆性:

Polyclonal (rabbit origin)