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折扣/货期| 货号：RQ5083 | 规格：100 ul | 目录价：￥6488.05 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Thymidylate Synthase Antibody
产品描述:
Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occurring antisense transcript, mitochondrial enolase superfamily member 1, vary inversely when cell-growth progresses from late-log to plateau phase. Polymorphisms in this gene may be associated with etiology of neoplasia, including breast cancer, and response to chemotherapy. [RefSeq]
反应种属:
Human, Mouse, Rat, Monkey
宿主来源:
Rabbit
实验应用:
WB
同种型:
Rabbit IgG
免疫原:
A synthetic peptide specific to human Thymidylate Synthase / TYMS was used as the immunogen for the Thymidylate Synthase antibody.
克隆性:
Rabbit Monoclonal
克隆号:
ADAA-20
纯化方式:
Affinity purified
保存温度:
Store the Thymidylate Synthase antibody at -20oC.
产品形式:
Purified
存储溶液:
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
产地:
美国
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