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折扣/货期| 货号：42734-10 mg | 规格：10 mg | 目录价：￥1300 |
| 货号：42734-25 mg | 规格：25 mg | 目录价：￥2720 |
| 货号：42734-5 mg | 规格：5 mg | 目录价：￥724 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Timapiprant (sodium salt)
别名:
OC000459
产品描述:
A DP2 receptor antagonist (Ki = 0.013 µM); selective for DP2 over DP1, TP, EP1-4, FP, and IP (Kis = >10 µM for all); inhibits calcium mobilization induced by PGD2 in CHO cells expressing human DP2 (IC50 = 0.028 µM); inhibits PGD2-induced Th2 T helper cell chemotaxis, IL-13 production, and apoptosis (IC50s = 0.028, 0.019, and 0.035 µM, respectively); reduces PGD2-induced blood eosinophilia in rats (ED50 = 0.04 mg/kg) and pulmonary eosinophil accumulation in guinea pigs (ED50 = 0.01 mg/kg); reduces Aβ plaque area and hippocampal microglial accumulation and improves learning and memory deficits in the TgF344 transgenic rat model of age-dependent and progressive Alzheimer’s disease
保存温度:
-20
运输温度:
-20
预期分子量:
347.369403
产品形式:
A solid
纯度:
≥98%
CAS号:
950688-14-9
分子式:
C21H16FN2O2 • Na
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