TIP60 (human) (rec.) (His) (highly active)-其他重组蛋白-深圳欣博盛生物科技有限公司

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TIP60 (human) (rec.) (His) (highly active)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-40T-0019-C002

规格：2 ug

目录价：￥2400

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

TIP60 (human) (rec.) (His) (highly active)

别名:

Histone Acetyltransferase HTATIP; Histone Acetyltransferase KAT5; Lysine Acetyltransferase 5; 60 kDa Tat-interactive Protein

产品描述:

TIP60 is the catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex is required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. TIP60 directly acetylates and activates ataxia-telangiectasia mutated (ATM). In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation.

宿主来源:

Sf21 cells

产品浓度:

Lot dependent (0.2-0.5mg/ml)

保存温度:

-20°C

运输温度:

产品形式:

liquid

存储溶液:

Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 0.2% NP-40, 50mM imidazole and 10% glycerol.

产地: