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折扣/货期| 货号：23319-1 mg | 规格：1 mg | 目录价：￥482 |
| 货号：23319-10 mg | 规格：10 mg | 目录价：￥1702 |
| 货号：23319-25 mg | 规格：25 mg | 目录价：￥3390 |
| 货号：23319-5 mg | 规格：5 mg | 目录价：￥1380 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Tipiracil (hydrochloride)
别名:
TPI
产品描述:
A thymidine phosphorylase inhibitor (IC50 = 35 nM); selective for thymidine phosphorylase over UPase, TK, OPRTase, and DPD (IC50s = > 1,000 µM for all); inhibits SARS-CoV-2 endoribonuclease nsp15 (IC50 = 7.5 µM); reduces the levels of SARS-CoV-2 spike glycoprotein in SARS-CoV-2-infected A549 cancer cells at 50 µM; prevents trifluorothymidine metabolism in human liver extracts at 1 µM; increases the plasma levels and potentiates the cytotoxicity of trifluorothymidine in an AZ-521 gastric carcinoma mouse xenograft model at an equimolar dose
保存温度:
-20
运输温度:
-20
预期分子量:
242.64
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
183204-72-0
分子式:
C9H11ClN4O2 • HCl
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