官网链接
折扣/货期| 货号：25981-10 mg | 规格：10 mg | 目录价：￥925 |
| 货号：25981-100 mg | 规格：100 mg | 目录价：￥2653 |
| 货号：25981-250 mg | 规格：250 mg | 目录价：￥4409 |
| 货号：25981-50 mg | 规格：50 mg | 目录价：￥1769 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Tirapazamine
别名:
3-Amino-1,2,4-benzotriazine 1,4-Dioxide|SR 259075|SR 4233|WIN 59075
产品描述:
A hypoxia-activated anticancer agent; is converted to an oxidizing radical under hypoxic conditions; can induce single- and double-strand breaks in DNA, formation of trapped topoisomerase I- and II-DNA complexes, and other chromosomal aberrations, leading to cytotoxicity; induces hypoxia-enhanced cytotoxicity in DT40 cells (IC50s = 1.02 and 4.34 μM in hypoxic and normoxic conditions, respectively); induces cytotoxicity in HT-1080 and A549 cells in a concentration-dependent manner under hypoxic conditions; sensitizes tumors to cisplatin in a mouse RIF-1 fibrosarcoma tumor model; sensitizes tumors to fractionated irradiation in a FaDu hypopharyngeal squamous cell carcinoma mouse xenograft model at (0.08 mmol/kg)
保存温度:
-20
运输温度:
-20
预期分子量:
178.2
产品形式:
A solid
纯度:
≥98%
CAS号:
27314-97-2
分子式:
C7H6N4O2
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询