深圳欣博盛生物科技有限公司 a1

Tirasemtiv
货号:26075-10 mg 规格:10 mg 目录价:¥询价
货号:26075-25 mg 规格:25 mg 目录价:¥询价
货号:26075-5 mg 规格:5 mg 目录价:¥询价
货号:26075-50 mg 规格:50 mg 目录价:¥询价
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Tirasemtiv
别名:
CK-2017357
产品描述:
An activator of the fast skeletal troponin complex; selectively binds to purified fast skeletal troponin complex (Kd = 40 nM) over slow skeletal (Kd = 3,800 nM) and cardiac troponin complexes; slows the rate of calcium release from the fast skeletal troponin complex at 20 μM; increases the ATPase activity of isolated rabbit fast skeletal myofibrils at a fixed calcium concentration (EC50 = 390 nM); sensitizes skinned fast skeletal muscle fibers isolated from human and rabbit to calcium; increases in situ EDL muscle force and forelimb grip strength in a rat model of myasthenia gravis; increases forelimb grip strength, grid hang test performance, and rotarod performance in a mouse model of ALS at 10 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
230.26592
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1005491-05-3
分子式:
C12H14N4O
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