| 货号:29016-1 mg | 规格:1 mg | 目录价:¥657 |
| 货号:29016-10 mg | 规格:10 mg | 目录价:¥5038 |
| 货号:29016-5 mg | 规格:5 mg | 目录价:¥2707 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
TMI-005
别名:
Apratastat
产品描述:
An inhibitor of ADAM17/TACE, MMP-1, and MMP-13 (IC50s = 20, 33, and 8.1 nM, respectively); inhibits LPS-induced TNF-α release in isolated human whole blood (IC50 = 144 ng/ml); reduces basal and ionizing radiation-induced secretion of ALCAM and amphiregulin from A549 and NCI H125 cells at 25 μM; inhibits proliferation of A549 at 25 and 50 μM; sensitizes A549 and NCI H125 cells to ionizing radiation at 25 μM; reduces tumor growth in an A549 mouse xenograft model when administered at 25 mg/kg twice per day in combination with ionizing radiation
保存温度:
-20
运输温度:
-20
预期分子量:
414.49846
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
287405-51-0
分子式:
C17H22N2O6S2
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