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折扣/货期| 货号：AG-CR1-2905-M005 | 规格：5 mg | 目录价：￥420 |
| 货号：AG-CR1-2905-M025 | 规格：25 mg | 目录价：￥1800 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
TOFA
别名:
RMI 14514; MDL 14514; 5-(Tetradecyloxy)-2-furoic acid; 5-(Tetradecyloxy)-2-furancarboxylic acid
产品描述:
Fatty acid synthase (FASN) inhibitor. Cell permeable, potent, reversible and competitive inhibitor of acetyl-CoA carboxylase (ACC) consequently blocking the synthesis of malonyl-CoA. Useful agent for immunometabolism research. Anticancer agent. Induces apoptosis in a variety of tumor cell lines. Relatively non-cytotoxic to various cancer cell lines. TOFA-induced reduction in malonyl-CoA is reported to off-set the effect of C75 (AG-CR1-2904) on food intake in fasted mice and on apoptosis in tumor cells. Hypolipidemic agent. Stimulates citrate accumulation in the cell, which leads to a suppression of glycolysis by citrate-induced inhibition of phosphofructokinase.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
324.5
产品形式:
solid
产地:
瑞士
纯度:
>98%
CAS号:
54857-86-2
分子式:
C19H32O4
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