| 货号:45457-1 mg | 规格:1 mg | 目录价:¥1327 |
| 货号:45457-10 mg | 规格:10 mg | 目录价:¥7960 |
| 货号:45457-25 mg | 规格:25 mg | 目录价:¥13266 |
| 货号:45457-5 mg | 规格:5 mg | 目录价:¥5306 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Tracazolate
别名:
ICI 136753
产品描述:
A positive allosteric modulator of the GABAA receptor; potentiates GABA-stimulated currents in X. laevis oocytes expressing α1β3γ2s and α1β1δ subunit-containing GABAARs (EC50s = 1.5 and 16.7 µM, respectively) and increases the maximal response to GABA in X. laevis oocytes expressing α1β1δ subunit-containing GABAARs, but reduces the maximal response to GABA in X. laevis oocytes expressing α1β3γ2s subunit-containing GABAARs; selectively potentiates GABA-induced currents in X. laevis oocytes expressing β3 over β1 subunit-containing GABAARs (EC50s = 1.5 and 13.2 µM for α1β3γ2s and α1β1γ2s subunit-containing GABAARs, respectively); increases time spent in social interactions but does not reduce locomotor activity, indicating anxiolytic but not sedating activity, in rats at 5 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
304.394
产品形式:
A solid
纯度:
≥98%
CAS号:
41094-88-6
分子式:
C16H24N4O2
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