官网链接
折扣/货期| 货号：25748-1 mg | 规格：1 mg | 目录价：￥1260 |
| 货号：25748-5 mg | 规格：5 mg | 目录价：￥2198 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Tropifexor
别名:
LJN452
产品描述:
An FXR agonist; enhances the interaction between the human FXR ligand binding domain and the SRC-1 peptide in an HTRF coactivator interaction assay (EC50 = 0.2 nM); increases expression of the FXR target genes BSEP and SHP and decreases expression of CPY8B1 in rat liver in a dose-dependent manner, as well as increases expression of SHP and FGF15 in rat ileum; reduces triglyceride levels by 79% in rat serum at 0.3 mg/kg; reduces fibrosis, inflammation, and steatosis in a mouse model of NASH
保存温度:
-20
运输温度:
-20
预期分子量:
603.585632
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1383816-29-2
分子式:
C29H25F4N3O5S
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