| 货号:F41609-0.08ML | 规格:0.08 ml | 目录价:¥2962.25 |
| 货号:F41609-0.4ML | 规格:0.4 ml | 目录价:¥6343.55 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
TRPM8 Antibody
产品描述:
Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. The chemical agonists menthol functions as a gating modifier, shifting activation curves towards physiological membrane potentials. Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing.
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB, IHC, ELISA
同种型:
Rabbit Ig
免疫原:
A portion of amino acids 69-98 from the human protein was used as the immunogen for this TRPM8 antibody.
克隆性:
Polyclonal (rabbit origin)
纯化方式:
Purified
保存温度:
Aliquot the TRPM8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
In 1X PBS, pH 7.4, with 0.09% sodium azide
产地:
美国
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