深圳欣博盛生物科技有限公司 a1

TS-011
货号:9002862-100 mg 规格:100 mg 目录价:¥3135.6
货号:9002862-250 mg 规格:250 mg 目录价:¥6566
货号:9002862-50 mg 规格:50 mg 目录价:¥1661.6
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
TS-011
产品描述:
An inhibitor of 20-HETE synthesis; inhibits 20-HETE synthesis in human and rat renal microsomes (IC50s = 8.42 and 9.19 nM, respectively), as well as by CYP4F2, CYP4F3A, CYP4F3B, and CYP4A11 in cell-free assays (IC50s = 30.4, 42.6, 43.0, and 188 nM, respectively); selective for these CYPs over CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4 (IC50s = >60 µM for all), as well as a panel of receptors and other enzymes at 1 µM; reverses decreases in cerebral blood flow and increases in cerebrospinal fluid 20-HETE levels in a rat model of subarachnoid hemorrhage from 0.01-1 mg/kg; reduces infarct volume and prevents neurological deficits in a rat model of MCAO-induced stroke
保存温度:
-20
运输温度:
-20
预期分子量:
255.70058
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
339071-18-0
分子式:
C11H14ClN3O2
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