深圳欣博盛生物科技有限公司 a1

Tunlametinib
货号:45050-1 mg 规格:1 mg 目录价:¥522.6
货号:45050-10 mg 规格:10 mg 目录价:¥2881
货号:45050-25 mg 规格:25 mg 目录价:¥5226
货号:45050-5 mg 规格:5 mg 目录价:¥1567.8
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Tunlametinib
别名:
HL 085
产品描述:
A MEK1 inhibitor; selective for MEK1 over a panel of kinases panel at 10 µM; selectively reduces proliferation in a panel of cancer cell lines expressing mutant K-Ras or B-RAF (IC50s = 0.67-59.89 nM) over H1975 cells expressing wild-type K-Ras and B-Raf (IC50 = >1,000 nM); inhibits ERK phosphorylation in A375 cells (IC50 = 1.16 nM); inhibits intratumoral ERK phosphorylation in an A375 mouse xenograft model at 1, 3, and 9 mg/kg; reduces tumor growth in an A375 mouse xenograft model at 3 and 9 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
491.251276
产品形式:
A solid
纯度:
≥98%
CAS号:
1801756-06-8
分子式:
C16H12F2IN3O3S
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