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折扣/货期| 货号：SBB-CE0021-C100 | 规格：100 ug | 目录价：￥4130 |
| 货号：SBB-CE0021-C050 | 规格：50 ug | 目录价：￥2296 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
UbcH5a/UBE2D1 (human) (rec.) (untagged)
别名:
Ubiquitin-conjugating Enzyme H5a; PUBC1; UBC5A; Ubiquitin-protein Ligase D1; p53-regulated Ubiquitin-conjugating Enzyme 1
产品描述:
UBE2D1 (UbcH5a) is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2D1 via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2D1-Ub thioester. UBE2D1 is capable of associating with numerous known E3 ligases which target abnormal proteins for proteasomal degradation through polyubiquitination. UBE2D1 is also known to interact with Parkin and to be involved in PINK1 mediated mitophagy.
宿主来源:
E. coli
产品浓度:
Lot dependent.
保存温度:
-80°C
运输温度:
Dry Ice
预期分子量:
~17kDa
产品形式:
liquid
存储溶液:
Liquid. In 50mM HEPES pH 7.5, 150mM sodium chloride, 10% glycerol (v/v), 2mM TCEP.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
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