深圳欣博盛生物科技有限公司 a1

UBCS039
货号:43478-1 mg 规格:1 mg 目录价:¥429
货号:43478-10 mg 规格:10 mg 目录价:¥4770
货号:43478-5 mg 规格:5 mg 目录价:¥2037
货号:43478-50 mg 规格:50 mg 目录价:¥9635
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
UBCS039
产品描述:
A SIRT6 activator; increases the deacetylation of an acetylated H3K9 peptide in a cell-free assay (EC50 = ~38 µM); selectively activates SIRT6 deacetylation activity over SIRT1, SIRT2, and SIRT3 deacetylation activities but does increase SIRT5 desuccinylation activity at 100 µM; active against M. tuberculosis (MIC = 50 µM); cytotoxic against a panel of six cancer cell lines (IC50s = 9.53-59.25 µM); decreases disease severity, hepatocyte apoptosis, and Ast, Alt, IL-1β, IL-6, and TNF-α serum levels in a mouse model of thioacetamide-induced acute liver failure at 50 mg/kg; increases the mean time to thrombotic occlusion in a mouse model of ferric chloride-induced arterial thrombosis at 2 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
247.301
产品形式:
A solid
纯度:
≥98%
CAS号:
358721-70-7
分子式:
C16H13N3
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