| 货号:RQ6217 | 规格:100 ug | 目录价:¥6488 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
UBE2D1/2/3/4 Antibody
产品描述:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene.
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
WB, IHC-P, IF, FACS, Direct ELISA
同种型:
Rabbit IgG
免疫原:
A human recombinant partial protein (amino acids D116-M147) was used as the immunogen for the UBE2D1/2/3/4 antibody.
克隆性:
Polyclonal (rabbit origin)
纯化方式:
Affinity purified
保存温度:
After reconstitution, the UBE2D1/2/3/4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
产品形式:
Antigen affinity purified
存储溶液:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
产地:
美国
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