Ubiquitin vinyl methyl ester (human) (rec.)-其他重组蛋白-深圳欣博盛生物科技有限公司

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Ubiquitin vinyl methyl ester (human) (rec.)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：SBB-PS0033-C050

规格：50 ug

目录价：￥3864

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Ubiquitin vinyl methyl ester (human) (rec.)

产品描述:

Ubiquitin is a small (8.5kDa) regulatory protein that has been found in almost all tissues of eukaryotic organisms. The addition of ubiquitin to a substrate protein is called ubiquitination or ubiquitylation. Ubiquitination can affect proteins in many ways: it can signal for their degradation via the proteasome, alter their cellular location, affect their activity and promote or prevent protein interactions. Removal of ubiquitin from a substrate protein occurs via deconjugating enzymes, of which there are nearly 100 known enzymes with various linkage specificities. This product consists of a full-length human, mature ubiquitin polypeptide (amino acids 1-76), expressed in E.coli with a C-terminal warhead (Vinyl Methyl Ester). Ubiquitin vinyl methyl ester is a potent, irreversible and specific inhibitor of deubiquitinating enzymes (DUBs) based on a C-terminal electrophilic vinyl methyl ester group. Ubiquitin vinyl methyl ester can be used for activity profiling experiments and determining DUB inhibitor specificity. It targets four of the five major DUB families: UCH (Ubiquitin C-terminal hydrolases), USP (Ubiquitin specific proteases), OTU (Ovarian tumor proteases) and MJD (Machado-Josephin domain proteases) while JAMM metalloproteases are not inhibited.

宿主来源:

E. coli

产品浓度:

Lot dependent.

保存温度:

-80°C

运输温度:

Dry Ice

预期分子量:

~9kDa

产品形式:

liquid