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折扣/货期| 货号：41056-1 mg | 规格：1 mg | 目录价：￥1273 |
| 货号：41056-10 mg | 规格：10 mg | 目录价：￥9514 |
| 货号：41056-25 mg | 规格：25 mg | 目录价：￥19014.6 |
| 货号：41056-5 mg | 规格：5 mg | 目录价：￥5708.4 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
UH15-38
产品描述:
A RIPK3 inhibitor (IC50 = 0.02 µM); selective for RIPK3 over a panel of 50 receptors and enzymes at 1 µM and a panel of 77 kinases at 0.5 µM but does inhibit RIPK1 (IC50 = 0.024 µM) and 13 other kinases by > 90% at 0.5 µM; inhibits LPS-induced necroptosis in RAW 264.7 macrophages and isolated mouse BMDMs (IC50s = 17 and 22 nM, respectively) and TNF-α-induced necroptosis in recombinant human RIPK3-expressing HeLa cells, FADD-/- Jurkat cells, and U937 cells (IC50s = 722, 205, and 329 nM, respectively); increases survival, decreases lung injury and immune cell BALF infiltration, and inhibits decreases in arterial oxygen saturation in a mouse model of severe influenza A infection at 30 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
441.52508
产品形式:
A solid
纯度:
≥95%
CAS号:
2540881-21-6
分子式:
C26H27N5O2
促销活动
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