深圳欣博盛生物科技有限公司 a1

Urocortin III (mouse) (trifluoroacetate salt)
货号:24750-1 mg 规格:1 mg 目录价:¥10157.2
货号:24750-500 µg 规格:500 µg 目录价:¥6767
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Urocortin III (mouse) (trifluoroacetate salt)
产品描述:
A neuropeptide hormone; expressed in the hypothalamus, brainstem, and LS/BnST as well as the small intestine, pancreatic β-cells, and skin in mice; selectively binds to type 2 CRF receptors (Kis = 5, 1.8, and >100 nM for rat CRF2α, rat CRF2β, and human CRF1, respectively); stimulates cAMP production in CHO cells expressing rat CR2α and mouse CR2β (EC50s = 0.073 and 0.08 nM, respectively); increases exploration in the open field test and decreases latency to enter the lit compartment in the dark-light emergence test, indicating anxiolytic-like activity in mice (20 μg, i.c.v); co-released with insulin to potentiate glucose-stimulated somatostatin release in vitro and in vivo in wild-type mice; depleted from β-cells in mouse and macaque models of type 2 diabetes
保存温度:
-20
运输温度:
-20
预期分子量:
4173.90348
产品形式:
A lyophilized powder
纯度:
≥95%
分子式:
C186H311N51O53S2 • XCF3COOH
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