官网链接
折扣/货期| 货号：14706-10 mg | 规格：10 mg | 目录价：￥965 |
| 货号：14706-100 mg | 规格：100 mg | 目录价：￥4569 |
| 货号：14706-25 mg | 规格：25 mg | 目录价：￥1595 |
| 货号：14706-5 mg | 规格：5 mg | 目录价：￥549 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Vandetanib
别名:
CH 331|Zactima|ZD 6474
产品描述:
A multi-kinase inhibitor that inhibits VEGFR2, VEGFR3, VEGFR1, EGFR, PDGFRβ, Tie-2, and FGFR1 (IC50s = 40, 110, 1,600, 500, 1,100, 2,500, and 3,600 nM, respectively, in cell-free assays); also binds to 142 additional kinases in a panel of 442 kinases (Kds = 4.6-7,900 nM); induces apoptosis and cell cycle arrest at the G0/G1 phase in GEO colon and OVCAR-3 ovarian cancer cells at 1 and 2.5 µM; inhibits proliferation of HAK1-B, KYN-2, and Huh7 hepatocarcinoma cells and HUVECs (IC50s = 10, 8.1, 9.4, and 7.1 µM, respectively); increases survival and decreases tumor angiogenesis and VEGFR2 levels in a D54MG glioblastoma mouse xenograft model at 200 mg/kg; reduces tumor growth in a variety of mouse xenograft models at 25-100 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
475.4
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
443913-73-3
分子式:
C22H24BrFN4O2
促销活动
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