VEGF R1 Recombinant Protein-细胞因子、趋化因子与生长因子-深圳欣博盛生物科技有限公司

首页产品中心细胞因子、趋化因子与生长因子

VEGF R1 Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：92-491

规格：0.05 mg

目录价：￥8125.65

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

VEGF R1 Recombinant Protein

别名:

Vascular endothelial growth factor receptor 1, VEGFR-1, Fms-like tyrosine kinase 1, FLT-1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor

表达系统:

Human Cells

保存温度:

Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.

运输温度:

Blue Ice

产品形式:

Lyophilized

存储溶液:

Lyophilized from a 0.2 um filtered solution of PBS,pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

产地:

美国

生产商:

Prosci

功能与背景:

Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 is widely expressed in human tissues including normal lung, placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cellsand peripheral blood monocytes. VEGFR-1 contains seven Ig-like C2-type domains and one protein kinase domain. VEGFR-1is an essential receptor tyrosine kinase and plays an important role in theregulation of VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. It is also mediators of neurotrophic activity and regulators of hematopoietic development. VEGFR-1 is a receptor for VEGF, VEGFB and PGF. It has a tyrosine-protein kinase activity. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF.It may play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells and promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific. VEGFR-1 can also promote PGF-mediated proliferation of endothelial cells, proliferation of some types of cancer cells, but does not promote proliferation of normal fibroblasts (in vitro).

纯度:

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

Accession #:

P17948

您可能感兴趣的产品

IL2 Recombinant Protein (e.coli Expressed)

货号：97-076

VEGF R2 Recombinant Protein

货号：97-070

EGF R Recombinant Protein

货号：97-063

EGF R Recombinant Protein