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折扣/货期| 货号：37925-1 mg | 规格：1 mg | 目录价：￥4409 |
| 货号：37925-5 mg | 规格：5 mg | 目录价：￥20931 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Vipoglanstat
别名:
BI 1029539|GS-248|OX-MPI
产品描述:
An mPGES-1 inhibitor (IC50 = ≤0.5 nM in isolated human whole blood); reduces LPS-induced increases in neutrophil influx and cytokine levels in BALF, as well as PTGES, Cox2, and Icam1 expression in the lung parenchyma, in a human PTGES knock-in mouse model of acute lung injury at 30 mg/kg; reduces the lung injury score and expression of PTGES and Nos2, as well as increases survival, in a human PTGES knock-in mouse model of cecal ligation and puncture-induced sepsis at 30 mg/kg; reduces status epilepticus-induced increases in brain capillary mPGES-1 and P-glycoprotein levels in a human PTGES knock-in mouse model of kainic acid-induced status epilepticus at 10, 30, and 100 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
678.520276
产品形式:
A solid
纯度:
≥98%
CAS号:
1360622-01-0
分子式:
C30H34Cl2F5N5O3
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