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折扣/货期| 货号：43577-1 mg | 规格：1 mg | 目录价：￥965 |
| 货号：43577-10 mg | 规格：10 mg | 目录价：￥6244 |
| 货号：43577-25 mg | 规格：25 mg | 目录价：￥9581 |
| 货号：43577-5 mg | 规格：5 mg | 目录价：￥3605 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
VT-1161
别名:
Oteseconazole
产品描述:
An antifungal agent; selectively binds to C. albicans lanosterol 14-α-demethylase (Kd = 39 nM), over human lanosterol 14-α-demethylase at 86 µM; does not inhibit human CYP2C9, CYP2C19, or CYP3A4 (IC50s = 99, 72, and 65 µM, respectively); decreases ergosterol levels and induces the accumulation of lanosterol, eburicol, 14α-methylfecosterol, and 14α-methylergosta-8,24(28)-dien-3β,6α-diol in C. albicans at 0.004 µg/ml; decreases vaginal lavage fluid levels of C. albicans in mouse models of fluconazole-sensitive and -resistant candidiasis at 25 mg/kg; binds to T. cruzi lanosterol 14-α-demethylase (Kd = 24 nM), is active against T. cruzi in vitro (EC50 = 2.5 nM), and reduces parasitemia in T. cruzi-infected mice at 50 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
527.402822
产品形式:
A solid
纯度:
≥98%
CAS号:
1340593-59-0
分子式:
C23H16F7N5O2
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