| 货号:18042-1 mg | 规格:1 mg | 目录价:¥482 |
| 货号:18042-10 mg | 规格:10 mg | 目录价:¥2492 |
| 货号:18042-25 mg | 规格:25 mg | 目录价:¥5628 |
| 货号:18042-5 mg | 规格:5 mg | 目录价:¥1380 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
VU0409551
别名:
JNJ-46778212
产品描述:
An mGluR5 PAM; induces calcium mobilization in HEK293 cells expressing human mGluR5 (EC50 = 260 nM); selective for mGluR5 over mGluR1-4 and mGluR6-8 at 10 μM; reverses amphetamine-induced hyperlocomotion in rats (ED50 = 23 mg/kg), indicating antipsychotic-like activity; increases levels of c-fos and expression of BDNF, Arc/Arg3.1, syntaxin 1A, and PSD-95 in the hippocampus in the BACHD mouse model of Huntington’s disease at 3 mg/kg; improves object location memory in the novel object location test and associative memory in the cued fear conditioning test in the BACHD mouse model at 3 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
352.4
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1363281-27-9
分子式:
C20H17FN2O3
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