官网链接
折扣/货期| 货号：23023-1 mg | 规格：1 mg | 目录价：￥844 |
| 货号：23023-10 mg | 规格：10 mg | 目录价：￥5253 |
| 货号：23023-25 mg | 规格：25 mg | 目录价：￥11082 |
| 货号：23023-5 mg | 规格：5 mg | 目录价：￥3243 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
WEHI-345
产品描述:
An inhibitor of RIPK2 (IC50 = 130 nM in a kinase assay using human recombinant RIPK2); selective for RIPK2 over RIPK1, 4, and 5 (Kds = 46, >10,000, >10,000, and >10,000 nM, respectively) and a panel of 95 kinases at a concentration of 1 μM; reduces levels of RIPK2 phosphorylation at Ser176 in MDP-stimulated BMDMs; decreases MDP-induced transcription of TNF and IL-6 in BMDMs and reduces mRNA levels of the NF-κB target genes TNF, IL-8, IL-1β, and A20 in MDP-stimulated THP-1 cells in a concentration-dependent manner; reduces plasma levels of TNF and delays disease onset in a mouse model of EAE when administered at doses ranging from 3-10 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
401.5
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1354825-58-3
分子式:
C22H23N7O
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