| 货号:29977-1 mg | 规格:1 mg | 目录价:¥710 |
| 货号:29977-10 mg | 规格:10 mg | 目录价:¥4100 |
| 货号:29977-25 mg | 规格:25 mg | 目录价:¥9380 |
| 货号:29977-5 mg | 规格:5 mg | 目录价:¥2251 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
WYE-687
别名:
WAY-687
产品描述:
An mTOR inhibitor (IC50 = 0.007 µM); selective for mTOR over PI3Kα and PI3Kγ (IC50s = 0.81 and 3.11 µM, respectively), as well as a panel of 24 additional kinases (IC50s = >50 µM for all); decreases phosphorylation of the mTORC1 and mTORC2 substrates Akt and S6K1, respectively, in a cell-free assay at 0.2, 1, and 5 µM; decreases proliferation of nine cancer cell lines (IC50s = 0.18-1.25 µM); inhibits survival of HL-60 and U937 leukemia cells; reduces tumor growth in a U937 mouse xenograft model at 5 and 25 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
528.6058
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1062161-90-3
分子式:
C28H32N8O3
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