深圳欣博盛生物科技有限公司 a1

WZ3146
货号:23440-1 mg 规格:1 mg 目录价:¥657
货号:23440-10 mg 规格:10 mg 目录价:¥5038
货号:23440-5 mg 规格:5 mg 目录价:¥2854
货号:23440-50 mg 规格:50 mg 目录价:¥13882
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
WZ3146
产品描述:
An inhibitor of mutant EGFRs (IC50s = 2-2,740 nM); selective for EGFR mutants including EGFRL858R and EGFRDel E746_A750 (IC50s = 2 nM for both) over wild-type EGFR (IC50 = 750 nM); inhibits ERBB2Ins G776V,C and wild-type ERBB2 (IC50s = 10 and 24 nM, respectively, in Ba/F3 cells) but not the ERBB2 gatekeeper mutant; decreases phosphorylation of EGFR, AKT, and ERK1/2 in H1975 NSCLC cells at 10-1,000 nM; inhibits proliferation of PC-9 and PC-9 GR cells (EC50s = 15 and 3 nM, respectively)
保存温度:
-20
运输温度:
-20
预期分子量:
465
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1214265-56-1
分子式:
C24H25ClN6O2
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