官网链接
折扣/货期| 货号：37749-10 mg | 规格：10 mg | 目录价：￥2171 |
| 货号：37749-25 mg | 规格：25 mg | 目录价：￥3725 |
| 货号：37749-5 mg | 规格：5 mg | 目录价：￥1152 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
XL092
别名:
Zanzalintinib
产品描述:
A multi-kinase inhibitor; selectively inhibits MET, VEGFR2, Axl, and Mer (IC50s = 3, 15, 5.8, and 0.6 nM, respectively) over serine/threonine kinases for which it has no activity, but does inhibit 28 additional RTKs (IC50s = 3-54 nM) and additional kinases by greater than 70% at 1 µM; inhibits the proliferation of SNU-5 cells (IC50 = 98.9 nM) and HUVECs (IC50 = 10.4 nM); reduces tumor volume and intratumoral MET phosphorylation in NCI H441 and SNU-5 mouse xenograft models at 3 and 10 mg/kg; increases the number of peripheral B cells and CD4+ T cells, and decreases the number of peripheral myeloid cells, in an MC-38 syngeneic mouse model of colon carcinoma at 30 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
528.531163
产品形式:
A solid
纯度:
≥98%
CAS号:
2367004-54-2
分子式:
C29H25FN4O5
促销活动
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