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折扣/货期| 货号：18464-1 mg | 规格：1 mg | 目录价：￥656.6 |
| 货号：18464-10 mg | 规格：10 mg | 目录价：￥2237.8 |
| 货号：18464-5 mg | 规格：5 mg | 目录价：￥1433.8 |
| 货号：18464-50 mg | 规格：50 mg | 目录价：￥7865.8 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
XL184
别名:
BMS-907351|Cabozantinib
产品描述:
A VEGFR2 inhibitor (IC50 = 0.035 nM); selective for VEGFR2 over Ron, EGFR, IGF-1R, and EphA4/B4; inhibits c-Met, RET, c-Kit, Axl, FLT3, and Tie2 (IC50s = 1.3, 5.2, 4.6, 7, 11.3, and 14.3 nM, respectively); inhibits VEGF-induced tubule formation in HMVECs at 4.6 nM; reduces HGF-induced migration and invasion of B16/F10 cells at 123 nM; induces tumor regression in an MDA-MB-231 breast cancer mouse xenograft model at 60 mg/kg; does not increase the number of pulmonary tumor foci in an MDA-MB-231 mouse metastasis model; protects primary placental fibroblasts from Zika virus infection
保存温度:
-20
运输温度:
-20
预期分子量:
501.5
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
849217-68-1
分子式:
C28H24FN3O5
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