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折扣/货期| 货号：29735 | 规格：1 mg | 目录价：￥4945 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
YM-254890
产品描述:
A cyclic depsipeptide Gαq/11 inhibitor; inhibits Gαq/11-mediated intracellular calcium mobilization induced by 2MeSADP or methacholine in C6-15 cells expressing the purinergic P2Y1 receptor (IC50 = 0.15 µM) and in CHO cells expressing M1 muscarinic acetylcholine receptors (IC50 = 0.15 µM), respectively; inhibits ADP-, collagen-, TRAP-, arachidonic acid-, or U46619-induced platelet aggregation in isolated human platelet-rich plasma (IC50s = 0.39, 0.15, 0.71, 0.25, and 0.34 µM, respectively); reduces shear stress-induced thrombus formation in isolated human whole blood; reduces platelet thrombus formation in a cynomolgus monkey model of femoral artery thrombosis at 1, 3, and 10 µg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
960.07824
产品形式:
A solid
纯度:
≥95%
来源:
Bacterium/Chromobacterium sp
CAS号:
568580-02-9
分子式:
C46H69N7O15
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