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折扣/货期| 货号：25452-1 mg | 规格：1 mg | 目录价：￥549 |
| 货号：25452-10 mg | 规格：10 mg | 目录价：￥4181 |
| 货号：25452-25 mg | 规格：25 mg | 目录价：￥8455 |
| 货号：25452-5 mg | 规格：5 mg | 目录价：￥2385 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
YU238259
产品描述:
An inhibitor of homology-dependent DNA repair; lethal to BRCA2-/- but not BRCA2+/+ PEO1/4 cells (LD50s = 8.7 and >100 μM, respectively); selectively inhibits HDR over NHEJ; decreases the number of U20S cells with ionizing radiation-induced BRCA1 foci but not 53BP1 or pDNA-PK foci; increases the number of ionizing radiation-induced DSBs in DLD-1 cells; cytotoxic to BRCA2-/- DLD-1, ATM-/- GM05849, and PTEN-/- U251 cells from 1-20 μM; delays tumor growth and increases survival in a BRCA2-/-, but not a BRCA+/+, DLD-1 mouse xenograft model at 3 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
459.9466
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
1943733-16-1
分子式:
C22H22ClN3O4S
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