| 货号:42444 | 规格:1 mg | 目录价:¥1849.2 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Z-FA-FMK
别名:
Cathepsin B Inhibitor|Z-Phe-Ala-Fluoromethyl Ketone
产品描述:
A cathepsin B inhibitor (Ki = 1.5 µM); inhibits caspase-2, -3, -6, -7, and -9 (IC50 = 6.147, 15.410, 32.45, 9.077, and 110.7 µM, respectively); inhibits SARS-CoV-2 Mpro in a cell-free assay (IC50 = 11.39 µM); inhibits SARS-CoV-2 replication in infected Vero E6 cells (EC50 = 0.13 µM) without inducing cytotoxicity in the same cells (CC50 = >20 µM); decreases the proliferation of, and levels of GSH in, and increases levels of ROS in anti-CD3-stimulated primary human PBMCs at 50 µM; inhibits LPS-induced increases in levels of IL-1β in PU5-1.8 macrophages and Nf-κB transactivation in Mf4/4 macrophages at 50 µM
保存温度:
-20
运输温度:
-20
预期分子量:
386.416803
产品形式:
A solid
纯度:
≥90%
CAS号:
96922-64-4
分子式:
C21H23FN2O4
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