官网链接
折扣/货期| 货号：35682-1 mg | 规格：1 mg | 目录价：￥4502 |
| 货号：35682-5 mg | 规格：5 mg | 目录价：￥13494 |
| 货号：35682-10 mg | 规格：10 mg | 目录价：￥20033 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Zasocitinib
别名:
NDI-034858|TAK-279
产品描述:
A TYK2 inhibitor; selectively binds to the TYK2 JH2 domain (Kd = 0.0038 nM) over the JAK1 and JAK2 JH2 domains (Kds = 4,975 and 23,000 µM, respectively); inhibits IFN-α-induced CXCL10 production in isolated human, mouse, and rat whole blood (IC50s = 22, 347, and 91 nM, respectively); inhibits IL-23-induced STAT3 phosphorylation in human CD161+CD3+ Th17 cells (IC50 = 3.7 nM); decreases ankle diameter in a rat model of adjuvant-induced arthritis at 3, 10, and 30 mg/kg twice per day; reduces the colon weight-to-length ratio and improves histology scores in a mouse model of anti-CD40 antibody-induced colitis at 30 and 90 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
460.48878
产品形式:
A solid
纯度:
≥98%
CAS号:
2272904-53-5
分子式:
C23H24N8O3
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