Zebrafish Sod2 Antibody / Superoxide dismutase 2-多抗-深圳欣博盛生物科技有限公司

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Zebrafish Sod2 Antibody / Superoxide dismutase 2

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：RZ1312

规格：100 ug

目录价：￥7788.55

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Zebrafish Sod2 Antibody / Superoxide dismutase 2

产品描述:

Zebrafish Sod2, also known as superoxide dismutase 2, is a manganese containing antioxidant enzyme located in the mitochondrial matrix. It catalyzes the dismutation of superoxide radicals into hydrogen peroxide and oxygen, which is a critical step in defending cells against oxidative stress generated during mitochondrial respiration. Sod2 is essential for maintaining mitochondrial integrity, reducing oxidative damage to proteins, lipids, and DNA, and ensuring proper cellular metabolism and survival.

Zebrafish Sod2 is an ortholog of the human SOD2 protein, with strong sequence and functional conservation. As in humans, Sod2 in zebrafish plays a vital role in protecting highly metabolic tissues such as the brain, heart, and muscles from oxidative damage. Mutations or reduced activity of Sod2 can lead to mitochondrial dysfunction and oxidative stress, contributing to developmental abnormalities and degenerative diseases.

Currently, there are no confirmed isoforms of zebrafish Sod2. It is broadly expressed across tissues but is particularly abundant in cells with high energy demands. Zebrafish models deficient in Sod2 have been used to investigate the consequences of oxidative imbalance and to explore therapeutic approaches aimed at reducing mitochondrial stress.

Antibodies targeting zebrafish Sod2 protein are important tools for studying mitochondrial antioxidant defense systems, oxidative signaling pathways, and stress responses. These antibodies can be utilized in western blot, immunohistochemistry, immunofluorescence, and ELISA to monitor Sod2 levels and localization in zebrafish tissues.

反应种属:

Zebrafish

宿主来源:

Rabbit

实验应用:

同种型:

Rabbit Ig

免疫原:

E. coli-derived zebrafish Sod2 recombinant protein (amino acids M1-K224) was used as the immunogen for the Zebrafish Sod2 antibody.

克隆性:

Polyclonal (rabbit origin)

纯化方式:

Antigen affinity chromatography

保存温度:

After reconstitution, the Zebrafish Sod2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

产品形式:

Antigen affinity purified

存储溶液:

0.5mg/ml if reconstituted with 0.2ml sterile DI water

产地:

美国

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