Zebrafish Srebf1 Antibody / Sterol regulatory element-binding protein 1-多抗-深圳欣博盛生物科技有限公司

首页产品中心多抗

Zebrafish Srebf1 Antibody / Sterol regulatory element-binding protein 1

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：RZ1315

规格：100 ug

目录价：￥7788.55

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Zebrafish Srebf1 Antibody / Sterol regulatory element-binding protein 1

产品描述:

Zebrafish Srebf1, also known as sterol regulatory element binding transcription factor 1, is a key regulator of lipid metabolism and homeostasis. Srebf1 is a transcription factor that controls the expression of genes involved in fatty acid, triglyceride, and cholesterol biosynthesis. By sensing lipid levels within the cell, Srebf1 activates metabolic pathways that ensure proper energy storage and membrane synthesis, which are essential during growth and development.

Zebrafish Srebf1 is an ortholog of the human SREBF1 protein, with strong sequence and functional conservation. Like its human counterpart, zebrafish Srebf1 is synthesized as an inactive precursor bound to the endoplasmic reticulum membrane. Upon sensing low sterol levels, the protein undergoes cleavage and translocation to the nucleus, where it binds sterol regulatory elements in target gene promoters to activate transcription.

The use of a Zebrafish Srebf1 antibody is valuable for detecting and analyzing the expression and processing of this protein in zebrafish tissues. Such antibodies are suitable for applications including western blot, immunohistochemistry, and immunofluorescence to study lipid metabolism and related regulatory pathways. A Zebrafish Srebf1 antibody can also be employed to monitor how dietary, genetic, or pharmacological factors influence lipid biosynthesis in zebrafish models.

There are currently no known isoforms of zebrafish Srebf1. The high degree of conservation between zebrafish and human Srebf1 makes this protein a relevant model for investigating metabolic disorders, including obesity, fatty liver disease, and cardiovascular disease. Using a high-quality Zebrafish Srebf1 antibody, researchers can explore conserved lipid regulatory mechanisms that have direct human health implications.

反应种属:

Zebrafish

宿主来源:

Rabbit

实验应用:

IHC-P

同种型:

Rabbit Ig

免疫原:

E. coli-derived zebrafish Srebf1 recombinant protein (amino acids H20-L1096) was used as the immunogen for the Zebrafish Srebf1 antibody.

克隆性:

Polyclonal (rabbit origin)

纯化方式:

Antigen affinity chromatography

保存温度:

After reconstitution, the Zebrafish Srebf1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

产品形式:

Antigen affinity purified

存储溶液:

0.5mg/ml if reconstituted with 0.2ml sterile DI water

产地:

美国

您可能感兴趣的产品