| 货号:38864-1 mg | 规格:1 mg | 目录价:¥2090 |
| 货号:38864-5 mg | 规格:5 mg | 目录价:¥8831 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
ZLY28
产品描述:
An FXR agonist and inhibitor of FABP1; selectively induces reporter gene expression in HepG2 cells expressing human FXR (EC50 = 143 nM) over cells expressing 19 other receptors (EC50s = >10,000 nM for all); selectively inhibits FABP1 (IC50 = 2.7 µM) over FABP3 (IC50 = >30 µM) but also inhibits FABP4 (IC50 = 6.3 µM); induces FXR-related gene expression in the ileum but not the liver in a mouse model of carbon tetrachloride-induced NASH at 20 mg/kg; reduces hepatocyte ballooning, as well as hepatic lobular inflammation and steatosis in the same model
保存温度:
-20
运输温度:
-20
预期分子量:
520.40266
产品形式:
A solid
纯度:
≥90%
CAS号:
3004676-77-8
分子式:
C29H23Cl2NO4
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