| 货号:GTX57563 | 规格:100μl | 目录价:¥5300 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
14-3-3 epsilon antibody [AT4F8]
别名:
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon , HEL2 , KCIP1 , MDCR , MDS , YWHAE , tyrosine 3monooxygenase/tryptophan 5monooxygenase activation protein epsilon , 14-3-3 epsilon , 1433E
反应种属:
Human, Mouse
宿主来源:
Mouse
实验应用:
ICC/IF, WB
靶标/特异性:
Based on internal testing result, this antibody does not cross react with human 14-3-3 zeta, human 14-3-3 beta, human 14-3-3 eta, human 14-3-3 gamma, human 14-3-3 sigma, and human 14-3-3 tau protein.
同种型:
IgG2b
免疫原:
The clone AT4F8 is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human 14-3-5 epsiilon protein.
克隆性:
Monoclonal
克隆号:
AT4F8
纯化方式:
Protein A Purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
29
产品形式:
Liquid
存储溶液:
PBS, 10% Glycerol, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]
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