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折扣/货期| 货号：AG-CR1-3596-G001 | 规格：1 g | 目录价：￥1440 |
| 货号：AG-CR1-3596-M250 | 规格：250 mg | 目录价：￥600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
3-Aminoisobutyric acid [BAIBA]
别名:
beta-Aminoisobutyric acid; BAIBA; 3-Amino-2-methylpropanoic acid; DL-3-Aminoisobutyric acid; alpha-Methyl-beta-alanine; 3-Aminoisobutanoate; 3-Aminoisobutyrate
产品描述:
Catabolite of thymine [1-4]. Precursor for 3-Hydroxyisobutyric acid synthesis [3]. Small molecule myokine. Browning inducer of white adipose tissue (WAT) into brown adipose tissue (BAT) [9, 10]. PGC-1alpha-mediated and exercise-triggered nonadrenergic activator of the thermogenic program in WAT. Increases the expression of brown adipocyte-specific genes (browning) in white adipocytes and beta-oxidation in hepatocytes through a PPARalpha-mediated mechanism [9, 10]. Induces a brown adipose-like phenotype in human pluripotent stem cells and improves glucose homeostasis [9, 10]. Enhances fatty acid oxidation and reduces body weight in mice through an increased production of leptin by the white adipose tissue (WAT) [5-7]. Inhibits Agxt2-mediated metabolism of dimethylarginines [8]. Partial agonist of the glycine receptor (GlyR) [4].
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
103.1 . 18.0
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
产地:
瑞士
纯度:
>98% (TLC)
CAS号:
214139-20-5 and 144-90-1 (anhydrous)
分子式:
C4H9NO2 . H2O
溶解度:
Soluble in DMSO or water.
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