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折扣/货期| 货号：79-891 | 规格：0.1 mg | 目录价：￥8213.4 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
4E-BP1 (phospho Thr70) Antibody
别名:
4EBP1, P/OKCL.6, P/OKCL.6, PHAS-I
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC
靶标/特异性:
The antibody detects endogenous levels of 4E-BP1 only when phosphorylated at threonine 70.
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
偶联:
Unconjugated
产品浓度:
1 mg/mL
保存温度:
Store antibody at -20˚C for up to one year.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
产地:
美国
生产商:
Prosci
功能与背景:
4E-BP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Accession #:
NP_004086.1
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