| 货号:AG-CR1-3525-M001 | 规格:1 mg | 目录价:¥420 |
| 货号:AG-CR1-3525-M005 | 规格:5 mg | 目录价:¥900 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
7-Azido-4-methylcoumarin
别名:
AzMC
产品描述:
Highly sensitive and selective fluorogenic H2S probe [1-3]. The aromatic azide moiety of AzMC is selectively reduced in the presence of H2S, producing the fluorescent 7-amino-4-methylcoumarin (AMC) with a concomitant increase in fluorescence with lambdaex = 365 nm and lambdaem = 450 nm. Photoaffinity labeling probe for the substrate binding site of human sulfotransferase 1A1 (SULT1A1). Probe to monitor the enzymatic production of H2S in vitro and to visualize H2S in living cells [2, 3]. Tool for monitoring the activity of pyridoxal-5'-phosphate (PLP)-dependent enzymes (e.g. cystathionine beta-synthase (CBS), cystathionine gamma-lyase (CGL) and tryptophan synthase (TS)) [2]. Tool to identify novel cystathionine beta-synthase (CBS) inhibitors and activators [2]. Suitable for high-throughput screening [2]. Caution: Use of this product with DTT, TCEP and/or biological thiols at concentrations of >25 mM should be avoided for maximum efficiency [2].
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
201.2
产品形式:
solid
产地:
瑞士
纯度:
>98% (NMR)
CAS号:
95633-27-5
分子式:
C10H7N3O2
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