| 货号:AG-CR1-3526-M001 | 规格:1 mg | 目录价:¥420 |
| 货号:AG-CR1-3526-M005 | 规格:5 mg | 目录价:¥1080 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
IHR-1
别名:
Inhibitor of Hedgehog Response 1; N,N'-1,4-Phenylene bis[2,5-dichloro-benzamide
产品描述:
Sonic hedgehog (Shh) signaling pathway inhibitor. Potential anticancer compound. Cell membrane impermeable Smoothened (Smo) antagonist. Acts on extracellularly exposed Smo only. Binds to the seven-transmembrane (7TM) pocket. Blocks hedgehog-induced movement of Smo into the primary cilium, disengages Smo-dependent abrogation of Gli2 and Gli3 proteolytic processing and inhibits Gli activity induced by loss of PTCH1.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
454.1
产品形式:
solid
产地:
瑞士
纯度:
>98% (NMR)
CAS号:
548779-60-8
分子式:
C20H12Cl4N2O2
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