深圳欣博盛生物科技有限公司 a1

A1874
货号:40842-1 mg 规格:1 mg 目录价:¥791
货号:40842-10 mg 规格:10 mg 目录价:¥6258
货号:40842-5 mg 规格:5 mg 目录价:¥3524
货号:40842-50 mg 规格:50 mg 目录价:¥13681
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
A1874
产品描述:
A PROTAC that drives BRD4 degradation; induces the degradation of BRD4, decreases the levels of c-Myc, and increases the levels of p53 and p21 in HCT116 cells at 10 µM; reduces proliferation of wild-type p53-expressing HCT116 and A375 cells but not p53 mutant-expressing NCI H2030 and HT-29 cells at 1 µM; decreases cell viability and induces cell cycle arrest at the G1 phase in, and reduces colony formation by, pCAN1 cells at 500 nM; decreases tumor volume, weight, and growth in a pCAN1 mouse xenograft model at 20 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
1173.590246
产品形式:
A solid
纯度:
≥95%
CAS号:
2064292-12-0
分子式:
C58H62Cl3F2N9O7S
在线留言
咨询类型
联系人
*
联系方式
*
单位名称
*
咨询内容
*
复制QQ号成功,请打开QQ后添加好友进行咨询